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  Article: An Easy Way to Eliminate Fatigue, Increase Energy - by Ward Dean, M.D.  
     
  Feeling fatigued? Run down? Have you tried everything to improve your energy levels? One solution you may have overlooked is improving the function of intracellular powerhouses in your body known as mitochondria. Even the slightest drop in mitochondrial energy output can lead to fatigue and difficulty concentrating. In fact, researchers have found malfunctioning mitochondria in fatigue patients.

    This article will show you which nutrients can improve your energy and eliminate your fatigue by improving mitochondrial function. People suffering from fatigue who have used this combination of mitochondrial-boosting nutrients have experienced an energy surge and an improvement in their concentration. Research indicates the following nutrients improve mitochondrial function and give sagging energy levels a lift.

Acetyl-L-Carnitine
As we age, mitochondria lose their power. In fact, one particular aspect of mitochondrial function works 40 percent less efficiently in old rats compared to young animals. In addition, levels of cardiolipin—a substance essential for proper mitochondrial functioning—decline with age.

In order to see if Acetyl-L-Carnitine (ALC) could improve mitochondrial function, researchers gave ALC to old mice.  Amazingly, ALC restored mitochondrial function and the amount of cardiolipin to levels seen in young animals.

N-Acetyl Cysteine
N-Acetyl Cysteine (NAC) improves the way the mitochondria's inner membrane functions. In addition, mitochondria feed upon the antioxidant glutathione.  Supplementation with the glutathione-boosting nutrient NAC assures plentiful levels of glutathione in the body.

Niacinamide (Vitamin B3)
Researchers at the National Aging Research Institute in Australia concluded that vitamin  B3 could re-energize the energy systems of old fruit flies. In fact, vitamin B3 extended the flies' lifespan by 15 percent.

Alpha Lipoic Acid
This antioxidant reverses age-related changes in the brains of animals. Lipoic acid improves the function of mitochondria, restoring it to youthful levels.

Succinate
    Succinate plays an important role in the functioning of the mitochondria's inner membrane. Patients suffering from diseases characterized by mitochondrial dysfunction have improved after treatment with succinates.  For instance, one patient with respiratory failure completely recovered after taking CoQ10 and sodium succinate. Based on the research, I believe that using magnesium and potassium succinates is even more effective than sodium succinate.

EDTA
Researchers recognized EDTA as early as the 1950s for its mitochondria-stabilizing abilities. Researchers have theorized that EDTA helps give the mitochondria a boost by positively impacting the mitochondrial membrane.

Other Mitochondrial-Boosting Agents
D-Ribose, creatine and taurine are also known to help the mitochondria keep their energy production at full steam. These three nutrients—and all the mitochondrial-boosting agents mentioned above—are found in Vitamin Research Product's MitoBoost I & II supplements. These agents work best when taken together with COQ10 and idebenone.

Conclusion
If you feel as if you're running on empty all the time, your mitochondria may be in need of some fuel. Although there are many sources of fatigue, mitochondrial dysfunction is an important cause of low energy. Supplementing with proper nutrients can jumpstart your intercellular powerhouses and restore vigor and vitality.
 
     
 

About the Author

Ward Dean, M.D. is author of the books Smart Drugs & Nutrients and The Neuroendocrine Theory of Aging and is an expert in anti-aging medicine. He is the Research and Development Director for Vitamin Research Products. To reach Dr. Dean or to find out more information about mitochondrial dysfunction, call 1-800-877-2447, visit the library at www.vrp.com or e-mail Dr. Dean at drdean@vrp.com. A complete list of references from medical journal articles referring to mitochondrial dysfunciton is available in the library at www.vrp.com.


 
 

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